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There are two main ways to avoid excessive interaction of the gut microbiota with TLRs to prevent activation of the intestinal and in some cases systemic immune response: i) decreasing the expression of TLRs, and ii) moving TLRs from the plasma membrane into lysosomes (Semin et al., 2021)

Glutathione is the major antioxidant in the body and reduces oxidative stress and inflammation

260 IndoHPYenHCNakanishiIMatsumotoKTamuraMNaganoYet al

5A and Supplementary Fig

Circadian variations in blood coagulation parameters, alpha-antitrypsin antigen and platelet aggregation and retention in clinically healthy subjects

doi: 10.1101/2024.10.20.619268v2 17 LiNRaghebKLawlerGSturgisJRajwaBMelendezJAet al