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Polystyrene (PS)-NPs of 100 nm can penetrate cells, including mouse embryonic fibroblasts (MEFs), where their accumulation leads to inflammation and oxidative stress (91,92)

Pericytes support neutrophil transmigration via interleukin-8 across a porcine co-culture model of the blood-brain barrier

Any shortage of active B6 (P-5-P), required by Glutamate Decarboxylase (GAD), further compromises production of GABA from glutamate

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This is because peptides are naturally occurring in your body, making it impossible for the FDA to patent something that your body makes on its own.