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The FDA has explicitly warned that botulinum toxin products from outside the approved US supply chain including those marketed as research grade or sourced from overseas compounders are not approved for human use and present serious risk of systemic botulism, which can cause difficulty breathing, swallowing, and speaking, and can be fatal

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3 At present, there are only a few reports of cosmetics-related NTM infection in China, and the incidence of cosmetics-induced NTM infection in China is unclear