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This is very important since copper is required for more than a dozen vital enzymes in the human body and skin including those that participate in connective tissue formation, antioxidant defense, and cellular respiration

Factors that can increase the risk of B12 deficiency include being over the age of 75, digestive absorption issues, autoimmune conditions, and certain diets like vegetarianism and veganism

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A.et al (2009)

A commonly encountered clinical scenario is a patient with CUC who presents with a cholestatic pattern of liver enzymes

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