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Both restrict blood flow and impair vascular health

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4.5 Obesity-associated bronchial vascular airway remodeling in asthma Several key factors are implicated in the initiation and progression of bronchial vascular remodeling, including the pro-inflammatory cytokines (309311), angiopoietin (312, 313), and growth factors specifically VEGF (314316)

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reported that over 85% of the 395 identified differentially expressed genes (DEGs) in islets from T2D donors were associated with regions of open chromatin or DNA methylation, with some overlapping T2D-associated single nucleotide polymorphisms (SNPs)

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