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10.1097/OPX.0000000000001826 25 ChakrabortyU.ChandraA

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It will be up to insurers to decide if they want to cover retatrutide prescriptions once it is FDA approved

Apoptosis is a caspase-dependent process activated by intrinsic (e.g., mitochondrial outer membrane permeabilization) or extrinsic (e.g., death receptor activation) stimuli

It also exhibits antioxidant properties, protecting cells from oxidative stress and reducing DNA damage

However, when activated by various pathological stimuli, including neurodegeneration, microglia can adopt a proinflammatory phenotype, leading to the release of cytokines, chemokines, and other mediators that perpetuate inflammation and contribute to neuronal loss [37,38]