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However, even a 50% reduction in worm burden would decrease the human health problems caused by schistosomiasis, and a combination of auranofin (or another TGR inhibitor) with an agent that works by a different mechanism might be more effective and would also reduce the chances of the parasite developing drug resistance

Bioavailability of oral hydroxocobalamin

3 days after the last treatment, blood samples were collected and centrifuged at 4000 rpm for 10 min at 4 C

ROS Overproduction: The Initiating Driver Hyperglycaemia activates multiple simultaneous ROS sources, including mitochondrial uncoupling, NADPH oxidase isoforms NOX2 and NOX4, and xanthine oxidase upregulation

The bacteriostatic agent effectively prevents bacterial growth, hence the term "bacteriostatic"