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Copper participates in the maturation of various neuropeptides, including neuropeptide Y and corticotropin-releasing hormone, both of which are vital for neuroprotection and modulating neuroinflammation after stroke (196, 199)

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They identified 20 characteristic microbial biomarkers that were significantly correlated with the clinical features of MN and constructed a predictive diagnostic model with an accuracy of 93.53%

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But at the same time and in the same lobule there may be cells with lesser injury, on the path to necrosis, but with hepatocytes that can be salvaged through interruption of the cycle of continued JNK activation and oxidative/nitrosative stress

doi:10.1101/gad.212282.112 Tobaben S, Grohm J, Seiler A et al (2011) Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons