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[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Pickart L, & Thaler MM

Sermorelin is not a weight loss medication, but some patients notice improvements in body composition when therapy is combined with proper nutrition and exercise

Common short-term side effects may include: Temporary water retention or bloating Mild joint stiffness or tingling Flushed skin or warmth at injection site Slight headache or fatigue (especially when beginning use) Peptide secretagogues like Ipamorelin appear to exhibit fewer adverse effects than GH or GHRH analogs and are highly selective for the GH axis (Smith et al., Journal of Endocrinological Investigation )

The researchers assessed markers related to proliferation, regeneration, aging, apoptosis, and extracellular matrix remodeling

All reported effects are observed in controlled in vitro and animal experiments