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Supplementary material The Supplementary Material for this article can be found online at: Abbreviations TMAU, trimethylaminuria

Trimethylamine N-oxide (TMAO) and N,N,N-trimethylglycine (betaine) are methylamine osmolytes that have been extensively studied for their diverse roles in humans and have demonstrated opposing relations with human health

Disruptions in circadian rhythms can adversely affect sleep quality and lead to imbalances in gut microbiota, resulting in alterations to the community structure, ecological parameters of the microbial ecosystem, and the inflammatory state of the body [45, 214,215,216,217,218,219,220,221]

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Copper Tripeptidehelps calm and soothe discomfort, building resilience in skin thats been weakened, promoting skin repair

Improved Exercise Performance: L-carnitine is well known for its ability to improve athletic performance by increasing the body's ability to use fat for energy during exercise