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TESTIMONIAL Real Stories

Efficacy and safety of subcutaneous versus intravenous bortezomib in multiple myeloma: a meta-analysis

FIGURE 4 Investigation Skin patch testing, lymphocyte transformation test (LTT), and ELISpot assay were three effective ways for finding the culprit drug for SCARs ( Multiple factors could affect the sensitivity and specificity of patch testing

Increased or decreased sensitivity with respect to therapeutic treatment is measured according to methods known in the art for the particular treatment and described below, including, but not limited to, cell proliferation assays (Tanigawa et al (1982) Cancer Res.42: 2159-2164) and cell death assays (Weissenthal et al (1984) Cancer Res.94: 161-173

Interestingly, in a mouse model of turpentine-induced tissue inflammation, high D3 expression in invading granulocytes has also been reported (157, 158)