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A Caenorhabditis elegans genome-scale metabolic network model

10.1111/ijfs.14459 40 PengC.SunW.DongX.ZhaoL.HaoJ

Farmer-Diaz K, M Matthew-Bernard, S Cheetham, D Fitzpatrick, K Mitchell, C Macpherson, and ME Ramos-Nino (2022)

By binding intestinal BAs and promoting their excretion, BASs reduce the BA pool returning to the liver, potentially decreasing BA-induced hepatotoxicity and altering systemic BA signals (134)

[] Taken together these data suggest that the claimed association between vitamin D deficiency and low testosterone could reflect nonbiological correlations due to similar distributions of shared risk factors and confounders