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Multi-pathway neuroprotective effects of a novel salidroside derivative SHPL-49 against acute cerebral ischemic injury

Inpatient Infusion Protocol In the inpatient setting, a continuous ketamine infusion can be initiated at 0.1 mg/kg/h and increased by 0.05 mg/kg/h hourly up to a rate of 0.25 mg/kg/h or until pain relief, nystagmus, or mild inebriation occurs

Lipopolysaccharide (LPS) released by Gram-negative bacteria activates TLR4 on Kupffer cells in the liver, promoting CXCL1 secretion and neutrophil recruitment (129, 130)

For the OCR assays in cells, culture medium was replaced with MAS buffer with 4% BSA, pH 7.2

Science 296:7992 Zhai CZ, Zhao L, Yin LJ, Chen M, Wang QY, Li LC, Xu ZS, Ma YZ (2013) Two wheat glutathione peroxidase genes whose products are located in chloroplasts improve salt and H 2 O 2 tolerances in Arabidopsis