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Vitamin B12 might amplify this effect by enhancing estrogen activity or synthesis through methylation-dependent pathways (27)

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But for those with severe pre-existing GERD, starting with semaglutide and its slightly gentler GI profile may be the more pragmatic choice

ACS Biomater Sci Eng 6:48704880

This ensures levels improve without becoming excessive

Non-parametric tests were used and the differences between two continuous variables were determined using Kruskal Wallis test