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However, in uncontrolled diabetics that have high blood glucose - more than the glycolysis pathway can handle - the reactions mass balance ultimately favors the production of sorbitol

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Disclosures: Chun-Ming Hong: Nothing to Disclose, Chih-Horng Wu: Nothing to Disclose, Tung-Hung Su: Nothing to Disclose, Shih-Jer Hsu: Nothing to Disclose, Tai-Chung Tseng: Nothing to Disclose, Chen-Hua Liu: Nothing to Disclose, Hung-Chih Yang: Nothing to Disclose, Jia-Horng Kao: Nothing to Disclose, Pei-Jer Chen: Nothing to Disclose, Shang-Chin Huang: Nothing to Disclose, Chun Jen Liu: Nothing to Disclose 1793 RESVERATROL AND TANSHINONE IIA SYNERGIZE TO SUPPRESS HEPATOCELLULAR CARCINOMA BY MODULATING STROMAL CELLS TO REMODEL TUMOR MICROENVIRONMENT Jia Shi 1 Xuemei Zhang 1 Xiaona Lu 1 Shihan Yu 1 Wenlan Zheng 1 Hai Feng 1 Zhuo Yu 2 , 1 Shuguang hospital Affiliated to SHUTCM, 2 Shuguang Hospital Affiliated to Shanghai University of TCM Background: Hepatocellular carcinoma (HCC) is usually insensitive to immunotherapy due to the aggravated immunosuppressive statue in context of liver fibrosis

Metformin, commonly prescribed for diabetes, and proton pump inhibitors used for acid reflux can both reduce B12 absorption over time

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The five bile acids (BAs) contributing most to each BA score are displayed in Figure 1