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The gcs2 gene was significantly upregulated in conidia from two strain backgrounds, being upregulated by 2.5-fold in ATCC200051 strain (Fig

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An increasing body of research suggests that lipid peroxidation products exacerbate degenerative muscle changes by inducing oxidative stress, disrupting cell membrane structures, impairing mitochondrial function, and regulating cell death pathways

Skin Issues: Some individuals experience skin problems, such as rashes or eczema, as a result of high oxalate levels

Additionally, validating lactylation signatures as liquid biopsy biomarkers is essential for patient stratification

PDIs can also react with GSH during thiol isomerization (Jessop and Bulleid, 2004), and may directly equilibrate with thioredoxin-related transmembrane protein 3 (TMX3) (Haugstetter et al., 2005)