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doi: 10.4049/jimmunol.2300847

Detection of deposited TCC (C5bC9) was done using a biotinylated mouse monoclonal antibody specific for a C9 neoepitope exposed upon C5b binding (Diatec Monoclonals, DIA 011-01) (diluted 1:5000 in PBS/T/S) together with AP-conjugated streptavidin (diluted 1:5000 in PBS/T/S) (Cytiva Life Sciences) and visualized by addition of AP substrate (Sigma-Aldrich)

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

it prevented low-density lipoproteins (LDL) oxidation to maintain normal cardiovascular and cardiac diastolic function, reducing cardiovascular adverse events (Garrido-Maraver et al., 2014)