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This unique metabolic dependency creates an exploitable therapeutic window between cancer cells and normal cells, potentially achieving more selective anti-cancer effects while reducing toxicity to normal tissues

GR can perform its enzymatic activity in the cytoplasm, but also in the ER and within lysosomes, mitochondria and the nucleus

a maternal T cell response was proposed as the reason for lower early engraftment rates in allogeneic IUSCT (Merianos et al., 2008)

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6 WHO Best Practices for InjectionsSubcutaneous injection technique, site preparation and rotation guidance

Carlsten C, MacNutt MJ, Zhang Z, Sava F, Pui MM