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The pathophysiology of IC/BPS is poorly understood, and theories include chronic inflammation, autoimmune dysregulation, bacterial cystitis, urothelial dysfunction, deficiency of the glycosaminoglycan (GAG) barrier and urine cytotoxicity

But its presence immediately begins breaking the peptide down

The decidua represents the maternal tissue most closely associated with the placental fetal unit

Learn more about this and which deficiencies are more likely to occur

Thus, we propose QMP engineering as a strategy to ensure a long plasma half-life and enhanced therapeutic efficacy of albumin fusion proteins despite C-terminal cleavage

Jego, G