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For investigational compounds such as retatrutide, reconstitution instructions are specified in the trial protocol and IMPD, and are followed by trained trial site staff

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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Yegneswaran B., Kostis J.B., Pitchumoni C.S

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Although clinical symptoms should receive more weight in diagnosing B12 deficiency, the panelists recognized the need to use serum vitamin B12 concentrations as a cost-effective screening marker and the need to additionally measure a metabolic marker to support the diagnosis