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Cu-chelating rescue agents, such as penicillamine derivatives, can be used for emergency intervention in cases of severe toxicity

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Also, GLP-1 receptor agonists were suggested to suppress OS generation induced by AGEs-RAGE and reduce tissue expression of RAGE via activation of cAMP pathways (79)

Genetic predisposition plays a significant role, although the exact genes involved are still being studied

Patient samples All human serum samples were obtained from the First Affiliated Hospital of China Medical University

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