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and (3) aminopropylation for polyamine synthesis

Besides importing from the extracellular environment, cells can synthesize serine from intracellular glucose through the de novo serine synthesis pathway (SSP), which is considered necessary for cancer cells (Locasale, 2013)

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Cultured RAW 264.7 treated with 16.7 g/mL FONE with catalase (0, 5 and 15 U/mL), or FONE70 (0, 16.7 and 20 g/mL), or 20 g/mL FONE70 with 3-AT (0, 5, and 15 U/mL) for 24 h were collected

Description 5-Amino-1MQ: Investigating the Bioenergetics of NNMT Inhibition 5-Amino-1MQ is a highly selective, membrane-permeable molecule designed to address metabolic dysfunction at the enzymatic level

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