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Conversely, cuproptosis, a copper-induced cell death triggered by the accumulation of Cu in mitochondria, leads to the aggregation of lipoylated dihydrolipoamide S-acetyltransferase (DLAT) and a loss of Fe-S protein, which are associated with energy formation in the tricarboxylic acid cycle (TCA), leading to proteotoxic cellular stress, eventually leading to cell death [7]
It protects your overall well-being by reducing oxidative stress, which is the cause of many diseases, including cancer
While generally considered safe, its important to consult with a qualified healthcare provider, especially if you have underlying health conditions or are taking other medications
Samples with different expression pattern are highlighted (yellow)
However, the connection between iron metabolism and T2D, along with its consequences, remained ambiguous until the identification of ferroptosis
