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Curculigo orchioides ethanolic extract have positive effect against human breast cancer line (MCF-7) at 10 g/ml and cancer forming tissues and it is also known to have been one of the anti-carcinogenic herb [85, 86]

In the human liver interactome, there is greater involvement of the proteins involved in lipid metabolism and various components involved in immune response activation and receptor-mediated endocytosis

Acknowledgments The authors acknowledges the use of Biorender that is used to create the figure

In the past 10 years, ferroptosis, an iron-dependent form of regulated cell death, has become increasingly recognized as an important process that mediates the pathogenesis and progression of numerous cardiovascular diseases, including atherosclerosis, drug-induced heart failure, myocardial ischaemiareperfusion injury, sepsis-induced cardiomyopathy, arrhythmia and diabetic cardiomyopathy

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Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus