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Lazo G, Kantarjian H, Estey E, Thomas D, OBrien S, Cortes J (2003) Use of arsenic trioxide (As2O3) in the treatment of patients with acute promyelocytic leukemia: the M.D

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All medications have the potential for side effects

Melatonins potential to strengthen the BBB appears to involve the upregulation of tight junction proteins, including claudin-5, zonula occludens-1, and occluding [191], which help shield the brain from harmful substances in the bloodstream [192]

Therefore, when assessing the health risks of MPs, it is essential to consider the combined effects of an individuals initial microbiota state, dietary structure, genetic susceptibility, and co-exposure to environmental factors (Fig