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Oral bioavailability, which is the measure of drug exposure in systemic circulation following oral dosing compared against IV dosing using AUC calculation, is critical to understanding if low systemic concentration comes from either poor absorption, first pass metabolism, or both (Yang et al., 2012)

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Safety is the number one priority when it comes to drinking alcohol, and driving is just one well-known area of risk

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Chen M, Neul C, Schaeffeler E, Frisch F, Winter S, Schwab M, Koepsell H, Hu S, Laufer S, Baker SD, et al

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