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Conducted in 5 countries, the study compared semaglutide 2.4 mg with placebo among 304 adults without diabetes who were obese or overweight and had at least 1 weight-related comorbidity

Serious ADR on long term use are Vitamin B12 deficency that leads to the anemia, lethergy along with numbness and tingling sensation in hands and feet, lactic acidosis in renal and hepatic impairment