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Animals were treated with DOX (8 mg/kg) once per week for 4 weeks, with ultrasound imaging every week to assess parameters of ( A ) left ventricular structure and ( B ) cardiac function

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The Clustal omega program was employed to perform protein sequence alignment ( Phylogenetic trees were constructed in MEGA 11, by the Neighbor-joining method using 1000 bootstraps as the phylogeny test for Gpx proteins, and by the Maximum Likelihood method using 500 bootstraps as the phylogeny test for Gst proteins

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