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The formation of such stable disulfide bonds in proteins in the ER is catalyzed by protein disulfide isomerase (PDI)

Nat Rev Endocrinol 15(6):323338

However, they are facing challenges in coordinating the individual components within the disordered diabetic wound microenvironment

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suggests that research models exposed to the peptide complex may have better bone formation around tendon cell grafts and a trend toward higher cell presence within the graft structure itself