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Furthermore, the strong correlation between pathological results of different ages and the level of MOTS-c suggests that higher MOTS-c is beneficial to delaying aging

Among the 226 patients who received cisplatin with pemetrexed, 74% received full supplementation with folic acid and vitamin B12 during study therapy, 14% were never supplemented, and 12% were partially supplemented

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For example, MTHFR gene variants and transcobalamin mutations can play a role