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Given that IGFs are involved in the regulation of cell metastasis, their roles in the metastasis and proliferation of cancer cells have been a focus of many studies in recent decades

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Studies completed in subjects on statins have yielded inconsistent results with regard to the importance of raising HDL-C partly due to evidence suggesting that statin (fluvastatin) use in low HDL-C subjects decreased coronary artery disease (CAD) with little to no increase in HDL-C levels (725-727)