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Description

GSH depletion induced by BSO deactivates GPX4, thereby elevating the ROS level in lipids, which is reflected by increased oxidation of NADPH and lysophosphatidylcholines (an indicator of lipid-producing ROS)

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Fahy, G.M., Brooke, R.T., Watson, J.P., Good, Z., Vasanawala, S.S., Maecker, H., & Bhatt, N

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XieLLiuGHuangZZhuZYangKLiangYet al

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The VPS13 gene family is involved in lipid transport to mitochondria and lysosomes [123], and VPS13 KO HeLa cells show increased cytosolic mtDNA levels and simultaneous cGAS-STING activation [122]

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Boosts Natural Energy Production L Carnitines primary biological function is energy production through fat oxidation

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Induction of ferroptosis using functionalized iron-based nanoparticles for anti-cancer therapy

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