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Numerous research studies have shown improved outcomes of combination treatments

For the 2013-2014 period covered in the Crime Commissions illicit drugs report, there was a 7.9% increase in drug seizures, with NSW accounting for 49.6% of seizures

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[PubMed: 9526807] 556

For example, Papokastas and colleagues 5 found that treatment of major depressive disorder (MDD) with 15mg of Lmethylfolate in conjunction with an SSRI showed significantly greater efficacy compared to SSRI therapy alone regarding response rate and degree of change in depression symptom scores

Participants were negative for HLA27 and none had clinical signs of spondyloarthritis or psoriasis