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We think that this is a good alternative to extrapolation to zero concentration, which introduces additional uncertainties, and to in-line measurements with size-exclusion chromatography (SEC-SAXS), where the technique leads to dilution and with laboratory-based SAXS to data of inferior quality 81

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Funding This study was supported by the Canadian Institutes of Health Research (grant number MOP-64345) and in part by the Ontario Ministry of Health and Long Term Care

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