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The combined use of Nm with 2F-, 2O-methoxy modifications, or phosphorothioate linkages reduced protein expression in cell lysates, yet such modified mRNA was still five times more efficient than unmodified RNA

doi: 10.1136/jnnp.23.1.56 69 YoungRCBiggsJTZieglerVEMeyerDA

However, it would be intriguing to determine if selenoprotein status correlated with monocyte CD16 expression

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For instance, estrogen may interfere with the cross-linking process, leading to a reduction in the mechanical integrity of collagen fibrils