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Another important mechanism is autophagy, the cellular waste-clearance process that helps remove misfolded proteins [97]

M1-like macrophages, induced by IFN- and TLR signaling, exhibit pro-inflammatory and cytotoxic functions, supporting antigen presentation and immune activation

Iron dysregulation in Huntingtons disease

Specifically, the cartilage exhibited a smooth articular surface with normal chondrocytes embedded within the typical cartilage matrix, surrounded by an intact synovial membrane