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They work through different mechanisms (GLP-1 and GIP receptor activation) and are FDA-approved prescription medications for type 2 diabetes and/or obesity management

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3 Results 3.1 The heterozygous mutation of EpCAM increased the sensitivity to the DSS-induced colitis To explore the impact of the heterozygous mutation of EpCAM on the intestinal immune homeostasis, the WT and EpCAM +/ mice were administrated with 3% DSS to induce the colitis as shown in Figure 1A