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Assessment of Chemotherapy-Induced Peripheral Neuropathy Using the LDIFLARE Technique: a Novel Technique to Detect Neural Small Fiber Dysfunction

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Indeed, the idea that chemotherapy accumulates in the human brain has been debated, and likely depends on the type of chemotherapy, the dose density, and other factors that may compromise the blood brain barrier (Screnci, McKeage et al., 2000), hypoxia, or lipopolysaccharide challenge (Minami et al., 1996a