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RowlandIGibsonGHeinkenAScottKSwannJThieleIet al

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J.HuynhL.et al

Studies have shown that silencing the anti-chondrogenic factor miR-221 can efficiently promote human BMSC chondrogenesis in vitro and in vivo , even without the need for the chondrogenic inducer TGF- ( Although some gene therapy applications have shown initial success, and the emergence of new gene editing technologies has brought IDD treatment to a new starting point, many obstacles still need to be overcome, such as safety concerns, high cost, and low transfection efficiency

Excess B12 may influence both bacterial activity and inflammation, which are key factors in acne development