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Description

Synthesis of a non-hydrolyzable estrone sulfate analogue bearing the difluoromethanesulfonamide group and its evaluation as a steroid sulfatase inhibitor

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Cyclic disulfide bond: Enhances molecular stability and prolongs half-life

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script in Supplementary Materials Scripts .zip file, BLASTn Query) search 35,36

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Valero F, Gonzlez-Mohno F, Salinero JJ

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Prolonged deficiency allows more extensive damage to accumulate, particularly to the nervous system, which requires longer to repair

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Davies (ed.), A Case-Based Guide to Clinical Endocrinology, 2008, pag.16 "Effect of Growth Hormone on Insulin Signaling"

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