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Si le disulfirame est bien un mdicament (en mdecine, un traitement peut agir soit en corrigeant un mcanisme biologique, soit en modifiant un comportement ou en prvenant une rechute), son utilisation soulve toutefois des questions thiques : elle nest acceptable que si le patient est clairement inform, volontaire et accompagn mdicalement

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Oxidative Stress-Related Biomarkers Oxidative stress has emerged as a pivotal pathophysiological mechanism underlying DPN, characterized by disrupted redox homeostasis resulting from excessive ROS generation and impaired antioxidant defense systems