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It was suggested that the strong anti-neuroinflammatory activity of the fresh ginger extract was largely contributed by 10-gingerol ( In addition, 6-, 8- and 10-gingerols/shogaols were shown to inhibit the canonical (NOD)-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome-mediated IL-1 secretion in ATP- and LPS-stimulated THP-1 macrophages

Xu M, Halimu G, Zhang Q, Song Y, Fu X, Li Y, Li Y, Zhang H

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