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PMC 4864755

Several hundred hemoglobinopathies caused by various mutations in globin genes are known, but only those associated with sickle cell disease are prevalent enough in the United States to merit discussion

In BV2 microglial cell lines subjected to lipopolysaccharide (LPS)-induced neuroinflammation, both lactylation-mediated inhibition of p53 activity and direct knockdown of p53 protein can disrupt the control of the NF-B inflammatory signaling pathway, ultimately leading to abnormal expression of pro-inflammatory factors and M1 polarization of microglia [132]

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About 63% and 28% of the papers published in the last 20 years, with this alga, were in the categories of Web of Science Environmental Sciences and Toxicology, respectively, while only ~ 3% were published in the category Biochemistry and Molecular Biology