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Temporal and spatial control: enables controlled drug release in time and space, improving treatment efficacy and safety

Gout attacks cause a characteristic painful inflammation of one or more joints of the extremities, or nodules in soft tissues called tophi

A double-blind study by Michaelsson et al 44 of 40 patients with moderate to severe acne demonstrated no significant difference between papule, pustule, and comedone count in subjects treated with oral zinc sulfate versus oxytetracycline for 12 weeks

Diarrhea May occur especially during dose adjustments

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Mild redness or swelling is completely normal and short-lived