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Since the guideline update in 2013, additional CFTR modulators have received FDA approval and continue to be a focus of research and development in CF management

A significant finding is miR-100s role in downregulating mTOR, a key driver of proliferation and therapy resistance in luminal breast cancer

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GPX4 inhibition enhances glioma radiosensitivity by inducing oxidative stress-dependent SSG and degradation of transglutaminase 2 (TGM2), impairing DNA repair 126

(2025) 5:50 doi: 10.3390/ruminants5040050 13