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PCS also induces apoptosis and autophagy by activating NF-B and MAPK signaling and increasing the phosphorylation of extracellular signal-regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK) in HK-2 cells ( Figure 3 ) [117]

Brain sections were stained with cresyl violet [34]

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Therefore, alteration of the GSH/GSSG ratio appears to be a common factor in the regulation of macrophage and cell-autonomous cellular inflammation

doi: 10.1126/science.aan3706 262 Kamierczak-SiedleckaKSkonieczna-ydeckaKHuppTDuchnowskaRMarek-TrzonkowskaNPoomK

Notably, conflicting findings have been reported regarding the abundance of certain bacterial taxa (e.g., Megasphaera and Barnesiella ), potentially due to population heterogeneity, methodological variability, or confounding factors such as constipation and allergies (Zhao et al., 2019