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doi: 10.3390/ijms22062973 67 HeitkemperMMHanCJJarrettMEGuHDjukovicDShulmanRJet al

In chronic illness, pro-inflammatory cytokines like Interleukin-6 (IL-6), Interleukin-1 beta (IL-1), and Tumor Necrosis Factor-alpha (TNF-) are chronically elevated

This therapy is a single intramuscular injection of a solution rich in B12 and folic acid aimed at reestablishing proper functioning levels

The most common side-effects were asthenia, fatigue, and cough, while the most frequent local adverse effects were oropharyngeal discomfort, nasal congestion, and pharyngalgia