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Description

MEK inhibition resulted in an increase in the pMEK signal due to multiple and opposing feedback loops from ERK and RSK

307 The interplay between mitophagy and obesity is complex, with mitophagy acting as both a protective and detrimental mechanism, depending on the context and extent of its activation

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The study found that daily supplementation with at least 400 IU of synthetic vitamin E (equivalent to 180 mg of RRR --tocopherol) resulted in a 4% increase in risk of death from any cause compared to placebo (125)