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Cell Culture HeLa cells were obtained from the Lerner Research Institute of the Cleveland Clinic Foundation (Cleveland, OH)

Sigma 1 receptor as a therapeutic target for amyotrophic lateral sclerosis

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In animal studies, metabolic improvements were observed over weeks to months, not days

& Dzamko, N

Safety, efficacy, and pharmacodynamics of the investigational agent orteronel (TAK-700) in metastatic castration-resistant prostate cancer (mCRPC): updated data from a phase I/II study [abstract 98]