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Moreover, G6PD expression was positively associated with microglial activation and dopaminergic neurodegeneration (245), indicating that oxidative stress is closely linked to neurodegeneration

[DOI] [PMC free article] [PubMed] [Google Scholar] Schinn S

Indeed, superoxide production has previously been demonstrated to be linked to the susceptibility of MNA NB cells to DPI, resulting in cytochrome c release, caspase activation, cytochrome c release and cell death (16)